Oxygenophilic Organoaluminum-Mediated Conjugate Addition of Alkyllithium and Grignard Reagents to Quinone Monoketals and Quinol Ethers. The Directing Effect of a Methoxy Group on the 1,4-Addition Process

Article abstract of DOI:10.1021/jo00279a033

Complexation of quinone monoketals and quinol ethers with methylaluminum bis(2,6-di-tert-butyl-4-methylphenoxide), the MAD reagent, followed by addition of organolithium or Grignard reagents gives products from 1,4-addition of the organometallic reagent t