CARBACEPHEMS AND 4-METHYLENE-AZETIDIN-2-ONES BY COPPER-,EDIATED AMIDE NITROGEN-VINYLIC CARBON RING CLOSURE

DOI: 10.1016/S0040-4039(00)95195-5

Source and publish data:

Tetrahedron Letters p. 337 - 340 (1989)

Update date:2022-08-02

Topics:

Authors:

Joyeau, R.

Kobaiter, R.

Sadet, J.

Wakselman, M.

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Article abstract of DOI:10.1016/S0040-4039(00)95195-5

Treatment of N-alkyl or N-aryl 3-bromo-3-buteneamides undeer modified Ullman-Goldberg conditions results in the direct formation of highly strained N-substituted 4-methylene-azetidin-2-ones in fair to good yields.In the same manner, 4-(4'-bromobuten-3'-enyl) azetidinone derivatives provides carbacephems.

Full text of DOI:10.1016/S0040-4039(00)95195-5

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