Penta- and hexadienoic acid derivatives: A novel series of 5-lipoxygenase inhibitors

DOI: 10.1021/jm00172a010

Source and publish data:

Journal of Medicinal Chemistry p. 2744 - 2749 (1990)

Update date:2022-08-04

Topics:

Authors:

Malleron

Roussel Roussel

Gueremy Gueremy

Ponsinet

Robin Robin

Terlain Terlain

Tissieres

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Article abstract of DOI:10.1021/jm00172a010

The synthesis of a series of pentadienoic ajnd hexadienoic acid derivatives is reported. These compounds were tested as inhibitors of 5-lipoxygenase (5 LO) and cyclooxygenase (CO) in vitro and as inhibitors of arachidonic acid (AA) induced ear edema in mi

Full text of DOI:10.1021/jm00172a010

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