Effect of N-Chloro Structure and 1-Substituent on ?-Substitution (Addition - Elimination) in Pyrroles

DOI: 10.1021/jo00283a032

Source and publish data:

Journal of Organic Chemistry p. 5347 - 5350 (1989)

Update date:2022-08-06

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Authors:

Rosa, Michael De

Nieto, Gustavo Cabrera

Gago, Fernando Ferrer

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Article abstract of DOI:10.1021/jo00283a032

1-Methylpyrrole was reacted with a number of different types of N-chloro derivatives, and ?-substitution was observed only with N-chloroimides.It is proposed that there is qualitative relationship between the pK_a of the N-chloro precursor and t

Full text of DOI:10.1021/jo00283a032

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