Journal of Medicinal Chemistry p. 77 - 86 (1990)
Update date:2022-09-26
Topics:
Albrecht, Harry A.
Beskid, George
Chan, Ka-Kong
Christenson, James G.
Cleeland, Roy
et al.
According to the generally accepted mechanism by which bacterial enzymes react with cephalosporins, opening of the β-lactam ring can lead to the expulsion of a 3'-substituent.A series of dual-action cephalosporins was prepared in which antibacterial quino
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