Synthesis and antirheumatic activity of novel tetrahydroquinoline-8-carboxylic acid derivatives

DOI: 10.1016/S0960-894X(97)00261-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1515 - 1518 (1997)

Update date:2022-09-26

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Authors:

Kohno, Yasushi

Awano, Katsuya

Miyashita, Mitsutomo

Fujimori, Shizuyoshi

Kuriyama, Kazuhiko

Sakoe, Yasuhiko

Kudoh, Shinji

Saito, Koji

Kojima, Eisuke

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Article abstract of DOI:10.1016/S0960-894X(97)00261-8

A study of the modification of N-alkylanthranilic acids to develop novel DMARDs is detailed. 1,2,3,4-Tetrahydroquinoline-8-carboxylic acid derivatives were found to exhibit a therapeutic effect on adjuvant arthritis and a suppressive effect on bone destruction.

Full text of DOI:10.1016/S0960-894X(97)00261-8

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Product name:8-QUINOLINECARBOXYLIC ACID, 1,2,3,4-TETRAHYDRO-6-NITRO-

Cas No:123296-82-2

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