Tetrahedron Letters p. 8769 - 8772 (1994)
Update date:2022-09-26
Topics: Synthesis Chiral Catalyst Nucleophilic addition Stereoselective Chemical Reaction Experimental Stereoisomer Styrene β-amino nitriles 1,3-diamines
Reetz, Manfred T.
Kayser, Frank
Harms, Klaus
Chiral β-N,N-dibenzylamino nitriles Bn2NCH(R)CH2CN, prepared in enantiomerically pure form from a-amino acids, can e deprotonated and stereoselectively alkylated to afford β-amino nitriles Bn2NCH(R)CH(R')CN with two stereo
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