Journal of Organic Chemistry p. 4812 - 4822 (1989)
Update date:2022-09-26
Topics:
Takahata, Hiroki
Takamatsu, Tamotsu
Yamazaki, Takao
Iodine-induced lactamization of γ,δ-unsaturated thioimidates proceeds regioselectively to provide γ-lactams.The iodolactamization with allylic substituents brings about 1,2-asymmetric induction, which depends on the allyl groups.Transformation of the cis-4-hydroxy-5-(iodomethyl)pyrrolidin-2-one (24a) among these highly functionalized γ-lactams into several biologically active compounds is described.In addition, the conversion of an optically active form of 24a is discussed.
View MoreYixing Bluwat Chemicals Co., Ltd.
Contact:+86 510 87821568
Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Changzhou Anyi Biochem Co., Ltd.(expird)
Contact:+86-519-88836158
Address:no,51 caoda
Contact:+1-284-4950244
Address:Box 3069, Road Town, Tortola, British Virgin Islands
Pure Chemistry Scientific Inc.
Contact:+1-857-366-7588
Address:14905 SW freeway street #232, Sugarland, TX 77478, USA
Yueyang Hudex Pharmaceuticals Ltd.
Contact:0730-8748800
Address:Wujiang Bridge，Yueyang Economy & Technology Development Zone
Doi:10.1016/j.bmc.2010.05.034
(2010)Doi:10.1021/jo00284a048
(1989)Doi:10.1021/om100039b
(2010)Doi:10.1021/op100097c
(2010)Doi:10.1246/cl.1999.615
(1989)Doi:10.1134/S1070363210040237
(2010)
