Synthesis of peptidyl fluoromethyl ketones and peptidyl α-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G

DOI: 10.1021/jm00163a063

Source and publish data:

Journal of Medicinal Chemistry p. 394 - 407 (1990)

Update date:2022-08-04

Topics:

Authors:

Peet Peet

Burkhart

Angelastro

Giroux Giroux

Mehdi Mehdi

Bey Bey

Kolb Kolb

Neises Neises

Schirlin

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00163a063

Comparison of MeO-Suc-Val-Pro-Phe-CO₂Me (29) and MeO-Suc-Ala-Ala-Pro-Phe-CO₂Me (25) with their corresponding trifluoromethyl ketones 9a and 9b, respectively, in rat and human neutrophil cathepsin G assays showed the α-keto esters to

Full text of DOI:10.1021/jm00163a063

Products guided by the article

Product name:4-Methyl-2-phenyl-4-(2,2,2-trifluoro-acetyl)-4H-oxazol-5-one

Cas No:123206-04-2

R&D Labs maybe for 123206-04-2

Wuxi Innopal International Trade CO.,LTD

Contact:+86-510-80711901-8003

Address:Room 402,Building 5,Longze Garden,No.17,South huanjiu Road,Yixing City, Jiangsu,China
Zhejiang Tianyu Pharmaceutical Co., Ltd.

Contact:+86-576-84177669, 89189665,89189688,84168770

Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Dalian RSD International Trade Co.,Ltd.(expird)

Contact:86-22-60875058 58610575

Address:Wantong International Areas, Hongqiao District, Tianjin, China.China
Xian Lyphar Biotech Co., Ltd.

Contact:0086-29-89196322

Address:North of the Fifth Keji Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China
Xiamen Kaijia Imp & Exp Co., Ltd.

Contact:86-592-5101177

Address:Room406 Luhui Building No. 65 Haitian Road Huli Xiamen,China.

Relevant to this article

Synthesis and conformational analysis of carbasugar bioisosteres of α-l-iduronic acid and its methyl glycoside

Doi:10.1016/j.carres.2010.03.002
(2010)
Photochemical formal alkadiene insertion into an aromatic C-CN bond using cyanide ion as a catalyst

Doi:10.1246/cl.2010.462
(2010)
Palladium(II) Complexes of NS Donor Ligands Derived from Steroidal Thiosemicarbazones as Antibacterial Agents

Doi:10.3390/molecules15074784
(2010)
Gold-catalysed room-temperature cycloisomerisation of alkynes and unactivated enolisable ketones

Doi:10.1039/c003473h
(2010)
Synthesis and oxidation of (4-hydroxy-3,5-di-tert-butylphenyl)- methanebis[diethyl(diphenyl)phosphine oxides]

Doi:10.1134/S1070363210030278
(2010)
5-[(Aminoalkyl)amino]imidazo[4,5,1-de]acridin-6-ones as a novel class of antineoplastic agents. Synthesis and biological activity

Doi:10.1021/jm00163a009
(1990)

Article Doi