Optical Resolution of Pantolactone by Inclusion Crystallization with (R,R)-(-)-trans-2,3-Bis(diphenylhydroxymethyl)-1,4-dioxaspirodecane, and Crystal Structure of the Resulting 1:1 Complex

Article abstract of DOI:10.1246/cl.1999.873

Pantolactone was resolved very efficiently by complex formation of its (S)-(-) isomer with the title host compound.The structure of the 1:1 complex was elucidated by X-ray crystallography.