Imidazo [4,5f][1,10] phenanthroline derivatives as inhibitor of c-myc gene expression in A549 cells via NF-κB pathway

DOI: 10.1016/j.bmcl.2011.11.063

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Bioorganic and Medicinal Chemistry Letters p. 102 - 105 (2012)

Update date:2022-08-03

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Authors:

Sun, Dong-Dong

Wang, Wei-Zhang

Mao, Jian-Wen

Mei, Wen-Jie

Liu, Jie

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Article abstract of DOI:10.1016/j.bmcl.2011.11.063

1,10-Phenanthroline has been shown to exhibit anticancer activity. Here, a series of imidazo [4,5f][1,10] phenanthroline derivatives 1-10 were synthesized and their biological activities were further elucidated. We found that 2-(4-Brominephenyl)-imidazo [

Full text of DOI:10.1016/j.bmcl.2011.11.063

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