Synthesis of the unusual α-amino acid component of some novel histone deacetylase inhibiting cyclic peptides

Article abstract of DOI:10.1016/j.tet.2014.07.045

A flexible protocol for the synthesis of three lipophilic α-amino acid components of some novel cyclic peptides having important histone deacetylase inhibiting properties has been developed from a common source, which featured a cross-metathesis reaction