"Umpolung" Using a Phosphorus Group. A Novel Method for the Chemoselective Synthesis of 2-Acetonyl or 3-Acetonyl Morpholines

DOI: 10.1055/s-1989-27232

Source and publish data:

Synthesis p. 301 - 303 (1989)

Update date:2022-08-04

Topics:

Authors:

Cristau, H. J.

Fonte, M.

Torreilles, E.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1989-27232

The substituted vinyltriphenylphosphonium salt 1 is shown to undergo chemoselective a⁴ addition with 2-aminoethanols 2 and 3 followed by intramolecular a⁴,a³-cyclization to give novel functionalized morpholines.

Full text of DOI:10.1055/s-1989-27232

Products guided by the article

Product name:2-<(2-Hydroxyethyl)benzylamino>-1-<(2-methyl-1,3-dioxolan-2-yl)methyl>ethyltriphenylphosphonium iodide

Cas No:123420-22-4

R&D Labs maybe for 123420-22-4

Zhejiang Sucon Silicone Co.,Ltd

Contact:+86-575-88046692

Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Hebei Fulong Import & Export Co., Ltd.

Contact:86-311-87795661

Address:15A19 Zhongyuan Building,368 Youyi North Street,Shijiazhuang 050070,China
Deltachem(QingDao)Co.,Ltd.

Contact:+8618766299236

Address:ROOM808, BUILDING2,NO.230 SHEN ZHEN ROAD, LAOSHAN DISTRICT
xujianqiang

Contact:86-21-57725962

Address:shanghai

Relevant to this article

Alkylation and aldol reactions of acyl derivatives of N-1-(1′-naphthyl)ethyl-O-tert-butylhydroxylamine: asymmetric synthesis of α-alkoxy-, α-substituted-β-alkoxy- and α,β-dialkoxyaldehydes

Doi:10.1016/j.tet.2010.03.105
(2010)
One-step transformation of tricyclopentabenzene (trindane, C(15)H(18)) to bicyclo(10.3.0)pentadec-1(12)ene- 2,6,7,11-tetrone (C(15)H(18)O(4)) and its aldol product, 12-hydroxy-16-oxatetracyclo(10.3.1.0.(1,5)0(7,11))hexadec-7(11)ene-2,6-dione (C(15)H(18)O(

Doi:10.1021/ol010086g
(2001)
Rate-dependent inverse-addition β-selective mannosylation and contiguous sequential glycosylation involving β-mannosidic bond formation

Doi:10.1002/asia.200900765
(2010)
A NEW METHOD FOR THE PREPARATION OF β-(ALKYLAMINO)-CARBONYL COMPOUNDS BY REARRANGEMENT OF β-CHLOROIMINES VIA AZETIDINE INTERMEDIATES

Doi:10.1016/S0040-4020(01)80122-8
(1989)
Highly Stereoselective Synthesis of syn-1,3-Diols through a Sequential Titanium-Mediated Aldol Reaction and LiBH₄ Reduction

Doi:10.1002/ejoc.201000293
(2010)
Synthesis of a novel α-galactosyl ceramide haptenated-lipid antigen, a useful tool in demonstrating the involvement of i NKT cells in the production of antilipid antibodies

Doi:10.1021/bc9005255
(2010)

Article Doi