Synthesis of 2-(pyrimidin-2-yl)-1-phenyl-2,3,4,9-tetrahydro-1H-β- carbolinesas antileishmanial agents

DOI: 10.1016/j.ejmech.2010.04.004

Source and publish data:

European Journal of Medicinal Chemistry p. 3274 - 3280 (2010)

Update date:2022-08-04

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Authors:

Kumar, Ravi

Khan, Shahnawaz

Verma, Aditya

Srivastava, Saumya

Viswakarma, Preeti

Gupta, Suman

Meena, Sanjeev

Singh, Neetu

Sarkar, Jayanta

Chauhan, Prem M.S.

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Article abstract of DOI:10.1016/j.ejmech.2010.04.004

A series of 2-(pyrimidin-2-yl)-1-phenyl-2,3,4,9-tetrahydro-1H-β- carboline derivatives has been synthesized and evaluated for antileishmanial activity against Leishmania donovani. Compound 8 exhibited best antileishmanial activity with IC₅₀ val

Full text of DOI:10.1016/j.ejmech.2010.04.004

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Product name:2-(4,6-dichloropyrimidin-2-yl)-1-(4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline

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