Tetrahedron Letters p. 4859 - 4862 (1988)
Update date:2022-08-05
Topics:
Barluenga, Jose
Fananas, Francisco J.
Foubelo, Francisco
Yus, Miguel
The successive reaction of different allylamines 1 with n-butyl-lithium,t-butyl-lithium, and diethyl carbonate at temperatures ranging between -50 and 20 deg C leads after hydrolysis to the corresponding α,β-unsaturated butyrolactams 3 in an one-pot process.
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