Synthesis of polyarylated methanes through cross-coupling of tricarbonylchromium-activated benzyllithiums

DOI: 10.1002/anie.201000957

Source and publish data:

Angewandte Chemie - International Edition p. 5541 - 5544 (2010)

Update date:2022-08-04

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Authors:

McGrew, Genette I.

Temaismithi, Jesada

Carroll, Patrick J.

Walsh, Patrick J.

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Article abstract of DOI:10.1002/anie.201000957

Support group: Coordinated to the tricarbonylchromium fragment, a typically unstable benzylic organolithium can participate directly in cross-coupling reactions with aryl bromides to form polyarylated methane derivatives (see scheme). Cr(CO)₃ assistance leads to reactivity with a variety of coordinated substrates and-given multiple benzylic sites-can effect up to six coupling events per arene. Chemical equation presented

Full text of DOI:10.1002/anie.201000957

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