Angewandte Chemie - International Edition p. 5502 - 5506 (2010)
Update date:2022-09-26
Topics:
Hara, Yuichi
Fujii, Taiga
Kashida, Hiromu
Sekiguchi, Koji
Liang, Xingguo
Niwa, Kosuke
Takase, Tomokazu
Yoshida, Yasuko
Asanuma, Hiroyuki
(Figure Presented) Excitonic interaction was utilized to design a highly sensitive in-stem molecular beacon (ISMB) in which both a fluorophore and a quencher on D-threoninols are incorporated as a pseudo base pair (see scheme; optimized combination with Cy3 and modified Methyl Red). Minimization of the difference between λmax of the fluorophore and quencher maximized quenching efficiency.
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(2010)Doi:10.1016/0022-328X(89)87310-3
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