
Tetrahedron p. 4007 - 4014 (1993)
Update date:2022-08-04
Topics:
Puertas
Brieva
Rebolledo
Gotor
Candida cylindracea lipase is a useful catalyst for the preparation of propiolamides. Candida antarctica lipase efficiently catalyzes the aminolysis of different acrylic esters and aliphatic amines; if racemic amines are used, the corresponding optically active acrylic amide is obtained in moderate-high enantiomeric excess.
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