Role of hydrogen bonding in ligand interaction with the N-methyl-D-aspartate receptor ion channel

DOI: 10.1021/jm00167a005

Source and publish data:

Journal of Medicinal Chemistry p. 1296 - 1305 (1990)

Update date:2022-09-26

Topics:

Authors:

Leeson Leeson

Carling Carling

James James

Smith Smith

Moore Moore

Wong Wong

Baker Baker

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00167a005

Displacement of [³H]MK-801 (dizocilpine, 1) binding to rat brain membranes had been used to evaluate the affinities of novel dibenzocycloalkenimines related to 1 for the ion channel binding site (also known as the phencyclidine or PCP receptor)

Full text of DOI:10.1021/jm00167a005

Products guided by the article

Product name:6-methyl-13-p-toluenesulphonyl-5,6,11,12-tetrahydrodibenzo[a,e]cycloocten-6,11-imine

Cas No:124853-21-0

R&D Labs maybe for 124853-21-0

Jinan Finer Chemical Co., Ltd

website:https://www.finerchem.com

Contact:+86-531-88989536

Address:New Material Industrial Park, Jinan City, China
Engineering Research Center of Pesticide, Heilongjiang Province

Contact:+86-451-86609001

Address:No.74 of Xuefu Road, Nangang District,
SuZhou Ascepion Pharmaceuticals, Inc.(expird)

Contact:0512-86881668

Address:Building C,68Xingqing Road,Suzhou,China.
CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD

website:http://www.czyys.com

Contact:0086-519-88802789

Address:No.300,Yanling Middle Road, Changzhou, Jiangsu, China
Jiangsu Institute of Ecomones Co., Ltd

website:http://www.jsmone.com

Contact:+86-519-82821700

Address:95 Huanyuan N. Road, Jintan, Jiangsu, China

Relevant to this article

Synthesis and structural features of sulfur-substituted calix[4]pyrrole for a bottom-up control of the substrate-directed self-assembly of supramolecular structures

Doi:10.1016/j.tet.2011.07.082
(2011)
Metal-free aerobic oxidative coupling of amines to imines

Doi:10.1039/c1cc13202d
(2011)
Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of pyridone-substituted piperidines

Doi:10.1016/j.bmcl.2011.05.013
(2011)
Synthesis of α,α-disubstituted aryl amines by rhodium-catalyzed amination of tertiary allylic trichloroacetimidates

Doi:10.1021/ol202313y
(2011)
Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors

Doi:10.1016/j.bmcl.2012.01.037
(2012)
Sulfur Nitride in Organic Chemistry. Part 19. Selective Formation of Benzo- and Benzobis<1,2,5>thiadiazole Skeleton in the Reaction of Tetrasulfur Tetranitride with Naphthalenols and Related Compounds

Doi:10.1246/bcsj.64.68
(1991)

Article Doi