Role of hydrogen bonding in ligand interaction with the N-methyl-D-aspartate receptor ion channel

DOI: 10.1021/jm00167a005

Source and publish data:

Journal of Medicinal Chemistry p. 1296 - 1305 (1990)

Update date:2022-09-26

Topics:

Authors:

Leeson Leeson

Carling Carling

James James

Smith Smith

Moore Moore

Wong Wong

Baker Baker

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00167a005

Displacement of [³H]MK-801 (dizocilpine, 1) binding to rat brain membranes had been used to evaluate the affinities of novel dibenzocycloalkenimines related to 1 for the ion channel binding site (also known as the phencyclidine or PCP receptor)

Full text of DOI:10.1021/jm00167a005

Products guided by the article

Product name:6-methyl-13-p-toluenesulphonyl-5,6,11,12-tetrahydrodibenzo[a,e]cycloocten-6,11-imine

Cas No:124853-21-0

R&D Labs maybe for 124853-21-0

Sichuan WeiKeqi Biological Technology Co., Ltd.

website:https://www.weikeqi-biotech.com/en

Contact:86-028-81700200

Address:sichuan Chengdu Qingjiang Zhonglu 63号
Shanghai Yuantai Chemical Products Co., Ltd

Contact:021--66129803

Address:Chengyin Road,Shanghai,China
Zha Yan

Contact:+86-13914766747

Address:Floors 21&22, Jin Cheng Tower, No. 216 Middle Longpan Road, Nanjing
shanghai Tauto Biotech Co., Ltd

website:http://www.tautobiotech.com/en/index.htm

Contact:+86-21-51320588 ext. 8025

Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
Yueyang Hudex Pharmaceuticals Ltd.

Contact:0730-8748800

Address:Wujiang Bridge，Yueyang Economy & Technology Development Zone

Relevant to this article

Synthesis and structural features of sulfur-substituted calix[4]pyrrole for a bottom-up control of the substrate-directed self-assembly of supramolecular structures

Doi:10.1016/j.tet.2011.07.082
(2011)
Metal-free aerobic oxidative coupling of amines to imines

Doi:10.1039/c1cc13202d
(2011)
Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of pyridone-substituted piperidines

Doi:10.1016/j.bmcl.2011.05.013
(2011)
Synthesis of α,α-disubstituted aryl amines by rhodium-catalyzed amination of tertiary allylic trichloroacetimidates

Doi:10.1021/ol202313y
(2011)
Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors

Doi:10.1016/j.bmcl.2012.01.037
(2012)
Sulfur Nitride in Organic Chemistry. Part 19. Selective Formation of Benzo- and Benzobis<1,2,5>thiadiazole Skeleton in the Reaction of Tetrasulfur Tetranitride with Naphthalenols and Related Compounds

Doi:10.1246/bcsj.64.68
(1991)

Article Doi