Synthesis p. 560 - 562 (1989)
Update date:2022-08-05
Topics:
Alvarez-Ibarra, Carlos
Mendoza, Magnolia
Orellana, Guillermo
Quiroga, Maria L.
A one-pot synthesis of 2-methylthio-1,3-oxazoles by a cyclocondensation reaction between dimethyl N-(ethoxycarbonylmethyl)iminodithiocarbonate and S-phenyl alkanethioates and thiobenzoates is described.The new procedure offers several advantages: easy access of the reagents, high selectivity, and facile introduction of different substitutions in the heterocyclic ring.
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Doi:10.1021/ja00030a039
(1992)Doi:10.1007/BF00956953
(1989)Doi:10.1007/BF00766389
(1989)Doi:10.1007/s10870-011-0101-z
(2011)Doi:10.1002/anie.201906805
(2019)Doi:10.1016/0022-328X(89)87020-2
(1989)
