Journal of the Chemical Society. Chemical communications p. 760 - 762 (1991)
Update date:2022-08-04
Topics:
Baker, Raymond
Street, Leslie J.
Reeve, Austin J.
Saunders, John
The synthesis of quinuclidine and azanorbornyl pyrazine derivatives has yielded highly potent and efficacious muscarinic agonists; chloro-substitution in the pyrazine ring of the quinuclidine analogue resulted in the formation of a derivative with both enantiomers displaying partial agonist character but, more importantly, functional selectivity at the M1, M2 and M3 sub-types of the muscarinic receptor.
View MoreContact:0086-22-23410962
Address:17-201, Ningfuli, Shuishanggongyuandong road,Nankai district, Tianjin, China
Shandong Zhongcheng Barium Salt Co., Ltd
Contact:+86-15725732638
Address:No.29 baoxi road, hi-tech zone, zibo, shandong
Contact:0086-29-89196322
Address:North of the Fifth Keji Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China
Contact:86-513-84128750/13773795976
Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
Contact:0086 371 65711996
Address:Jalan 4/3, Kawasan Perindustrian Serendah, 48000 Rawang,
Doi:10.1039/c0cc02604b
(2010)Doi:10.1016/j.jfluchem.2009.05.019
(2009)Doi:10.1016/j.dyepig.2012.05.015
(2012)Doi:10.1039/c6ra06682h
(2016)Doi:10.1016/j.bmc.2012.06.018
(2012)Doi:10.1007/s11172-009-0342-6
()
