SYNTHESIS OF TRICHOSTATIN A, A POTENT DIFFERENTIATION INDUCER OF FRIEND LEUKEMIC CELLS, AND ITS ANTIPODE

DOI: 10.1016/S0040-4020(01)89789-1

Source and publish data:

Tetrahedron p. 6013 - 6020 (1988)

Update date:2022-09-26

Topics:

Authors:

Mori, Kenji

Koseki, Koshi

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Article abstract of DOI:10.1016/S0040-4020(01)89789-1

Both the enantiomers of trichostatin acid (1, 98percent e.e.) and trichostatin A (2, 93percent e.e.) were synthesized employing methyl (R)- or (S)-3-hydroxy-2-methyl-propanoate as a starting material.

Full text of DOI:10.1016/S0040-4020(01)89789-1

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