ACS Combinatorial Science p. 375 - 380 (2014)
Update date:2022-08-02
Topics: Reaction scheme Workup
Bogolubsky, Andrey V.
Moroz, Yurii S.
Mykhailiuk, Pavel K.
Panov, Dmitriy M.
Pipko, Sergey E.
Konovets, Anzhelika I.
Tolmachev, Andrey
A parallel reductive amination of heteroaromatic amines has been performed using a combination of ZnCl2-TMSOAc (activating agents) and NaBH(OAc)3 (reducing agent). A library of diverse secondary amines was easily prepared on a 50-300 mg scale.
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