Journal of Medicinal Chemistry p. 1491 - 1496 (1990)
Update date:2022-08-04
Topics: Synthesis IC50 HPLC (high-performance liquid chromatography) Analogues Biological Evaluation Structure-Activity Relationship (SAR) Anti-Inflammatory Spectroscopic Analysis In vitro assay Inhibiting activity Hindered phenols
Aizawa, Yuichi
Kanai, Tsutomu
Hasegawa, Kazuo
Yamaguchi, Takeshi
Iizuka, Yoshio
et al.
A series of hindered phenolic 1,3-benzoxathioles (7a-1) were prepared and investigated for biological properties.Many compounds had LPO-lowering, antisuperoxide inhibiting, SRS-A inhibiting, and 5-lipoxygenase inhibiting activities.Among them, 5-hydroxy-4
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Doi:10.1248/cpb.38.1246
(1990)Doi:10.1002/cmdc.201000276
(2010)Doi:10.1039/c0cc02836c
(2010)Doi:10.1002/chem.201501271
(2015)Doi:10.1002/chem.201001748
(2010)Doi:10.1002/ardp.201000016
(2010)
