The Synthesis and Antibacterial Activities of Quinolones Containing Five- and Six-Membered Heterocyclic Substituents at the 7-Position

Article abstract of DOI:10.1021/jm00166a025

A series of 6-fluoro-7-substituted-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids were prepared.The substituents at the 7-position included five- and six-membered heterocyclic rings such as oxazoline and oxazine as well as five-membered heteroaroma