Asymmetric syntheses of 1-alkyltetrahydro-β-carbolines and a 9-thio analogue

DOI: 10.1248/cpb.39.3338

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3338 - 3340 (1991)

Update date:2022-08-05

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Authors:

Qais Qais

Nakao Nakao

Hashigaki

Takeuchi

Yamato Yamato

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Article abstract of DOI:10.1248/cpb.39.3338

Tetrahydro-β-carbolines, (S)-tetrahydroharman (8a) and (S)-1-phenyltetrahydro-β-carboline (8b), were asymmetrically synthesized starting from (R)-phenylglycinol and 1-benzyl-3-(2-bromoethyl)indole (1). Asymmetric synthesis of the 9-thio analogue (15) of 8

Full text of DOI:10.1248/cpb.39.3338

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