Antifungal activity of morinol B derivatives of tetrahydropyran sesquilignan

DOI: 10.1271/bbb.100422

Source and publish data:

Bioscience, Biotechnology and Biochemistry p. 2071 - 2076 (2010)

Update date:2022-09-26

Topics:

Authors:

Masuda, Kenta

Nishiwaki, Hisashi

Akiyama, Koichi

Yamauchi, Satoshi

Maruyama, Masafumi

Sugahara, Takuya

Kishida, Taro

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Article abstract of DOI:10.1271/bbb.100422

The relationship between the structure of naturally occurring (7R,70R,8R,80R)-morinol B and its antifungal activity was examined. 3-Demethoxy morinol B showed much higher activity than the natural compound. The activity of the 4-butoxy-3-demethoxy derivative was higher than that of 3-demethoxy morinol B.

Full text of DOI:10.1271/bbb.100422

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