Use of human-milk fucosyltransferase in the chemoenzymic synthesis of analogues of the sialyl Lewisx and sialyl Lewisa tetrasaccharides modified at the C-2 position of the reducing unit

Article abstract of DOI:10.1016/0008-6215(93)84162-Y

Two series of trisaccharides, having the formulas α-Neu5Ac-(2->3)-β-D-Gal-(1->4)-β-D-GlcZ-OR and α-Neu5Ac-(2->3)-β-D-Gal-(1->3)-β-D-GlcZ-OR respectively, in which the 2-deoxy substituent Z is azido, amino, propionamido, or acetamido, were