
Journal of Pharmaceutical Sciences p. 188 - 192 (1985)
Update date:2022-09-26
Topics:
Pedersen
FitzGerald
Inhibition of endogenous prostacyclin and thromboxane biosynthesis by aspirin is critically dose-dependent in humans. Gastrointestinal and hepatic hydrolysis may limit systemic availability of aspirin, especially in low doses, perhaps contributing to the
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