Synthesis and structure-activity relationships of 2-(4-benzhydryl-1-piperazinyl)-1-phenylethanols as new calcium blockers

DOI: 10.1248/cpb.43.241

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 241 - 246 (1995)

Update date:2022-09-26

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Authors:

Nomura Nomura

Yamakawa

Nishioka

Omura Omura

Miyake Miyake

Masaki Masaki

Nohira Nohira

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Article abstract of DOI:10.1248/cpb.43.241

A series of 2-(4-benzhydryl-1-piperazinyl)-1-phenylethanols (4) was synthesized and evaluated for calcium entry-blocking activity, assessed as inhibitory activity on calcium current in rat hippocampal pyramidal neurons by using a patch-clamp technique (10

Full text of DOI:10.1248/cpb.43.241

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