Synthesis and structure-activity relationships of 2-(4-benzhydryl-1-piperazinyl)-1-phenylethanols as new calcium blockers

DOI: 10.1248/cpb.43.241

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 241 - 246 (1995)

Update date:2022-09-26

Topics:

Authors:

Nomura Nomura

Yamakawa

Nishioka

Omura Omura

Miyake Miyake

Masaki Masaki

Nohira Nohira

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.43.241

A series of 2-(4-benzhydryl-1-piperazinyl)-1-phenylethanols (4) was synthesized and evaluated for calcium entry-blocking activity, assessed as inhibitory activity on calcium current in rat hippocampal pyramidal neurons by using a patch-clamp technique (10

Full text of DOI:10.1248/cpb.43.241

NII-Electronic Library Service

Products guided by the article

Product name:2-(4-benzhydryl-1-piperazinyl)-1-(2,3,4-trimethoxyphenyl)ethanone

Cas No:126713-05-1

R&D Labs maybe for 126713-05-1

Chemsky（shanghai）International Co.,Ltd.

Contact:0

Address:0
Pengchen New Material Technology Co., Ltd.

Contact:+86-512-63680537

Address:99.6 km of national road 318, Meiyan Community,Pingwang Town, Wujiang District, Suzhou 215225
Amadis Chemical Co., Ltd.

website:http://www.amadischem.com

Contact:86-571-89925085

Address:Watts Cosine.No.166.Xiangmao Road.
Chinese Peptide Company

Contact:86-571-86737118-8689

Address:No.69, 12 Street, HEDA, Hangzhou, Zhejiang, China
Jinan Finer Chemical Co., Ltd

website:https://www.finerchem.com

Contact:+86-531-88989536

Address:New Material Industrial Park, Jinan City, China

Relevant to this article

Approaches to the total synthesis of phomactins

Doi:10.1016/S0040-4039(03)00341-1
(2003)
Structural revision in the reactions of 3-cyanochromones with primary aromatic amines. Improved synthesis of 2-amino-3-(aryliminomethyl)chromones

Doi:10.1016/j.tetlet.2009.09.028
(2009)
Palladium-catalyzed formation of secondary and tertiary amines from aryl dihalides with air-stable ferrocenyl tri- and diphosphines: Synthesis and X-ray structure of efficient catalysts beyond [PdCl₂(DPPF)]

Doi:10.1016/j.catcom.2014.03.012
(2014)
Synthesis of hexopyranosyl acetates and 2,3-disubstituted tetrahydropyrans via chemoselective hydrogenation of hex-2-enopyranosyl acetates

Doi:10.1016/j.tetlet.2006.09.091
(2006)
Vanadium-based imido-alkoxide pro-catalysts bearing bisphenolate ligands for ethylene and ε-caprolactone polymerisation

Doi:10.1039/b902402f
(2009)
Decarboxylative ketone aldol reactions: Development and mechanistic evaluation under metal-free conditions

Doi:10.1021/jo901022j
(2009)

Article Doi