Chemical and pharmaceutical bulletin p. 2679 - 2682 (1989)
Update date:2022-09-26
Topics:
Landelle
Laduree
Cugnon de Sevricourt
Robba
Cyclization reaction of hydrazine with carbazole-2,3-methyl dicarboxylates gave 1,4-dioxo-1,2,3,4-tetrahydropyridazino[4,5-b]carbazoles. Chlorodehydroxylation provided 1,4-dichloropyridazino[4,5-b]carbazoles and nucleophilic substitution gave 1,4-dialkoxy pyridazino[4,5-b]carbazoles. These compounds were tested for cytotoxic activity against L1210 leukemia in mice.
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Doi:10.1016/S0040-4039(01)93373-8
(1989)Doi:10.1016/S0040-4039(01)93912-7
(1989)Doi:10.1039/d0ob01124j
(2020)Doi:10.1248/cpb.37.3114
(1989)Doi:10.1016/j.molstruc.2010.12.026
(2011)Doi:10.1039/c39900000327
(1990)
