Journal of Heterocyclic Chemistry p. 1349 - 1352 (1989)
Update date:2022-08-03
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Jurd
Mannich bases of types 1 or 8, which are readily synthesized by condensation of 3,4-methylenedioxyphenol with aromatic aldehydes and pyrrolidine or piperazine, react with cyclic and acyclic β-diketones to yield benzopyrans. These benzopyrans are structurally similar to podophyllotoxin and like this drug some of the benzopyrans show in vivo anti-leukemic action in mice.
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Doi:10.1016/S0040-4039(01)93814-6
(1989)Doi:10.1021/jo00297a031
(1990)Doi:10.1002/chem.201404692
(2014)Doi:10.1016/j.bmc.2010.11.053
(2011)Doi:10.1021/jo00299a036
(1990)Doi:10.1016/S0040-4039(00)76009-6
(1994)
