Asymmetric synthesis of a lignan lactone from a meso anhydride

DOI: 10.1016/0040-4020(96)00761-2

Source and publish data:

Tetrahedron p. 12799 - 12814 (1996)

Update date:2022-08-04

Topics:

Authors:

Ward, Robert S.

Pelter, Andrew

Edwards, Mark I.

Gilmore, Jeremy

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Article abstract of DOI:10.1016/0040-4020(96)00761-2

The synthesis of a meso-2,3-dibenzylbutanedioic acid anhydride is given. Reaction of this with (+)-α-methylbenzylamide proceeds diastereoselectively to give a butanedioic acid monoamide which is converted into an enantiomerically enriched cis-2,3-dibenzyl

Full text of DOI:10.1016/0040-4020(96)00761-2

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Product name:racem.-2.3-bis-(3.4-dimethoxy-benzyl)-succinic acid dimethyl ester

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