Manganese(III)-Based Oxidative Free-Radical Cyclization of Unsaturated β-Keto Esters, 1,3-Diketones, and Malonate Diesters

DOI: 10.1021/jo00295a035

Source and publish data:

Journal of Organic Chemistry p. 2427 - 2436 (1990)

Update date:2022-08-04

Topics:

Authors:

Kates, Steven A.

Dombroski, Mark A.

Snider, Barry B.

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Article abstract of DOI:10.1021/jo00295a035

Oxidative free-radical cyclizations of unsaturated β-keto esters, 1,3-diketones, and malonate diesters with 2 equiv of Mn(OAc)3*2H2O and 1 equiv of Cu(OAc)2*H2O are described.Oxidation of β-keto ester 1 with Mn(III) to enol radical 2 followed by 6-exo cyc

Full text of DOI:10.1021/jo00295a035

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