Dual-action cephalosporins: Cephalosporin 3'-quaternary ammonium quinolones

DOI: 10.1021/jm00106a031

Source and publish data:

Journal of Medicinal Chemistry p. 669 - 675 (1991)

Update date:2022-08-02

Topics:

Authors:

Albrecht

Beskid Beskid

Christenson

Durkin Durkin

Fallat Fallat

Georgopapadakou

Keith Keith

Konzelmann

Lipschitz

McGarry McGarry

Siebelist

Wei Wei

Weigele Weigele

Yang Yang

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00106a031

When cephalosporins exert their biological activity by reacting with bacterial enzymes, opening of the β-lactam ring can lead to expulsion of the 3'-substituent. A series of cephalosporins was prepared in which antibacterial quinolones were linked to the

Full text of DOI:10.1021/jm00106a031

Products guided by the article

Product name:(6R-trans)-4-<3-carboxy-6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxoquinolin-7-yl>-1-<<2-carboxy-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-en-3-yl>methyl>-1-methylpiperazinium iodide

Cas No:127142-75-0

R&D Labs maybe for 127142-75-0

Chengdu CSH Pharmaceutical Co.,ltd

Contact:+86-(28)-85321971

Address:Block B,New Hope Int. Tian Fu New District, Chengdu, Sichuan, China
HANGZHOU ZHONGCHANG SCIENTIFIC CO.,LTD

Contact:+86-571-88932183

Address:Hangzhou
Shanghai Longjin Metallic Material Co., Ltd.

website:http://www.shlongjin.cn/

Contact:021-56517503,56502257

Address:No.16, Lane 555, Chengyin Road, Shanghai
Jiangxi Huashi Pharmaceutical Co., Ltd

Contact:+86-795-4509628

Address:No.199, Ningbo Avenue, Fengxin industrial park, Fengxin county, Yichun city, Jiangxi
Hunan Haili Chemical Industry Co.,Ltd.

Contact:+86-731-85521860

Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China

Relevant to this article

REARRANGEMENT OF 5-HYDROXY-1-(4-TOLYL)-4-N-METHYLCARBAMOYL-1,2,3-TRIAZOLE TO 5-HYDROXY-1-METHYL-4-N-(4-TOLYL)-CARBAMOYL-1,2,3-TRIAZOLE

Doi:10.1007/BF00962474
(1989)
Synthesis, anticancer activity, and iron affinity of the Actinoplanes metabolite 7,8-dihydroxy-1-methylnaphtho[2,3-c]furan-4,9-dione

Doi:10.1016/j.bmc.2010.12.012
(2011)
The synthesis of some carbaprostacyclin precursors

Doi:10.1016/S0040-4020(01)89508-9
(1989)
Cyclic RGD β-Lactam Peptidomimetics Induce Differential Gene Expression in Human Endothelial Cells

Doi:10.1002/cbic.201000572
(2011)
Pd-catalyzed asymmetric reactions using resorcinol- and hydroquinone-based P,P-bidentate diamidophosphites

Doi:10.1016/j.tetlet.2010.11.111
(2011)
Ultrasound assisted dehydrogenation of 2-oxo-1,2,3,4-tetrahydropyrimidine- 5-carboxamides

Doi:10.1016/j.ultsonch.2010.10.006
(2011)

Article Doi