1,2-Addition of Sulfur Nucleophiles to the N-Acylated Imine Linkage. A Model Study for the Incorporation of Sulfur Nucleophiles during Metabolism of Acylated Aromatic Amines

DOI: 10.1021/jo00300a002

Source and publish data:

Journal of Organic Chemistry p. 3969 - 3971 (1990)

Update date:2022-07-29

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Authors:

Clark, William M.

Swenton, John S.

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Article abstract of DOI:10.1021/jo00300a002

The imine linkage of an acylated quinone imine ketal reacts with ethanethiol to afford an isolable addition product which subsequently rearranges by a facile 1,2-shift to afford an ortho-substituted aromatic amide.

Full text of DOI:10.1021/jo00300a002

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