Glycosyl α-amino acids via stereocontrolled buildup of a penaldic acid equivalent. A novel synthetic approach to the nucleosidic component of the polyoxins and related substances

DOI: 10.1021/jo00299a017

Source and publish data:

Journal of Organic Chemistry p. 3772 - 3787 (1990)

Update date:2022-08-02

Topics: Stereocontrolled Synthesis

Authors:

Garner Garner

Park Park

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00299a017

A novel approach to glycosyl α-amino acids is exemplified by the stereocontrolled and asymmetric synthesis of thymine polyoxin C (4) from the known (serine-derived) penaldic acid equivalent 5. The overall synthetic strategy involves four distinct phases:

Full text of DOI:10.1021/jo00299a017

Products guided by the article

Product name:1,1-Dimethylethyl*,R^*),4R>>-1-<α-methoxy-α-(trifluoromethyl)-α-phenylacetyl>-4-(4,4-dimethoxy-2-butynyl)-2,2-dimethyl-3-oxazolidinecarboxylate

Cas No:127308-65-0

R&D Labs maybe for 127308-65-0

Chengdu Chengnuo New-Tech Co., Ltd

Contact:0086-028-85749078

Address:4 Jiuyang road,Jiulong industrial port,Chengdu, China
Beijing Harmony Chemical Co., Ltd.

Contact:86-010-84956928

Address:Room 207, Jin feng he B building, No 8 Xin Jie Kou Wai Street, Xi Cheng District, Beijing,PRC. 10008
Junkai (Tianjin) Chemical Co., Ltd.

website:http://www.junkaichem.com

Contact:86-22-85689515

Address:Room 8-501, Building K2, The Hi-Tech Green Industrial Base, No.6, 6th Road, Hi-Tech Development Road, Tianjin Hi-Tech IndustrialPark, Tianjin, China.
XinChem Corporation

Contact:+86 21 34123252

Address:14, 4580 Dushi, Shanghai, China
Beijing eternalchem Co,. Ltd

Contact:+86-10-59484199

Address:No.58-A1026 Liangguan Street

Relevant to this article

Carbonyl complexes of molybdenum and tungsten with sulfur donores VI. Reactions of carbonyl complexes of molybdenum(0) and tungsten(0) with uninegative (S,X)-donor ligands (X = S, N, P).

Doi:10.1016/0022-328X(90)87055-I
(1990)
Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox

Doi:10.1002/cctc.201701379
(2017)
Decarboxylative Addition of Propiolic Acids with Indoles to Synthesize Bis(indolyl)methane Derivatives with a Pd(II)/LA Catalyst

Doi:10.1021/acs.joc.1c00762
(2021)
A NOVEL AMINO ACID ANTIBIOTIC TAN-950

Doi:10.1016/S0040-4020(01)91004-X
(1991)
Characterization of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP-glucuronosyltransferases

Doi:10.1111/j.1476-5381.2010.01104.x
(2011)
SUBSTITUTED 4-(1',2'-ALKADIENESULPHINYL)-MORPHOLINES; PREPARATION AND HYDROLYTIC DESULPHINYLATION INTO THE CORRESPONDING ALKYNES

Doi:10.1016/S0040-4039(01)80555-4
(1989)

Article Doi