Glycosyl α-amino acids via stereocontrolled buildup of a penaldic acid equivalent. A novel synthetic approach to the nucleosidic component of the polyoxins and related substances

DOI: 10.1021/jo00299a017

Source and publish data:

Journal of Organic Chemistry p. 3772 - 3787 (1990)

Update date:2022-08-02

Topics: Stereocontrolled Synthesis

Authors:

Garner Garner

Park Park

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Article abstract of DOI:10.1021/jo00299a017

A novel approach to glycosyl α-amino acids is exemplified by the stereocontrolled and asymmetric synthesis of thymine polyoxin C (4) from the known (serine-derived) penaldic acid equivalent 5. The overall synthetic strategy involves four distinct phases:

Full text of DOI:10.1021/jo00299a017

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