Glycosyl α-amino acids via stereocontrolled buildup of a penaldic acid equivalent. A novel synthetic approach to the nucleosidic component of the polyoxins and related substances

DOI: 10.1021/jo00299a017

Source and publish data:

Journal of Organic Chemistry p. 3772 - 3787 (1990)

Update date:2022-08-02

Topics: Stereocontrolled Synthesis

Authors:

Garner Garner

Park Park

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00299a017

A novel approach to glycosyl α-amino acids is exemplified by the stereocontrolled and asymmetric synthesis of thymine polyoxin C (4) from the known (serine-derived) penaldic acid equivalent 5. The overall synthetic strategy involves four distinct phases:

Full text of DOI:10.1021/jo00299a017

Products guided by the article

Product name:1,1-Dimethylethyl*,R^*),4R>>-1-<α-methoxy-α-(trifluoromethyl)-α-phenylacetyl>-4-(4,4-dimethoxy-2-butynyl)-2,2-dimethyl-3-oxazolidinecarboxylate

Cas No:127308-65-0

R&D Labs maybe for 127308-65-0

zhenjiang runjing high purity chemical co ltd

Contact:+86-511-83361155

Address:No.8.haixi road,international chemical park
Nantong LiKai Chemical Co.,Ltd

Contact:+86-513-89068669

Address:Jincheng Science Park
Deer Chemicals Co., Ltd.

Contact:+86-13666670345

Address:Agricultural Development Zone, Haining, Jiaxing, Zhejiang
Nanjing lanbai chemical Co.,Ltd.

Contact:+86-25-85499326

Address:Room 908, 9F Taiyue Building,No.285 Heyan Road
QINGDAO HONG JIN CHEMICAL CO.,LTD.

website:http://www.hongjinchem.com

Contact:+86-532-83657313

Address:2ND Building, 8 Shangqing Road, Qingdao, Shandong Province, China.

Relevant to this article

Carbonyl complexes of molybdenum and tungsten with sulfur donores VI. Reactions of carbonyl complexes of molybdenum(0) and tungsten(0) with uninegative (S,X)-donor ligands (X = S, N, P).

Doi:10.1016/0022-328X(90)87055-I
(1990)
Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox

Doi:10.1002/cctc.201701379
(2017)
Decarboxylative Addition of Propiolic Acids with Indoles to Synthesize Bis(indolyl)methane Derivatives with a Pd(II)/LA Catalyst

Doi:10.1021/acs.joc.1c00762
(2021)
A NOVEL AMINO ACID ANTIBIOTIC TAN-950

Doi:10.1016/S0040-4020(01)91004-X
(1991)
Characterization of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP-glucuronosyltransferases

Doi:10.1111/j.1476-5381.2010.01104.x
(2011)
SUBSTITUTED 4-(1',2'-ALKADIENESULPHINYL)-MORPHOLINES; PREPARATION AND HYDROLYTIC DESULPHINYLATION INTO THE CORRESPONDING ALKYNES

Doi:10.1016/S0040-4039(01)80555-4
(1989)

Article Doi