Turkish Journal of Chemistry p. 859 - 867 (2010)
Update date:2022-07-30
Topics:
Korkusuz, Elif
Yildirim, Ismail
The 1H-pyrazole-3-carboxylic acid 2 was converted via reactions of its acid chloride 3 with various hydroxylamine 4a-f and carbazate derivatives 8a-c into the corresponding novel N-substituted-4-benzoyl-1,5-dipenyl-1 H-pyrazole-3-carboxamides 5a-c, N, N-disubstituted-4-benzoyl-1,5-diphenyl-1 H-pyrazole-3-carboxylates 6d,e, 4-benzoyl-N-{[(4-benzoyl-1,5-diphenyl-1H- pyrazol-3-yl)carbonyl]oxy}-N-methyl-1,5diphenyl-1 H-pyrazole-3-carboxamide (7), and 4-benzoyl-N′-(alkoxycarbonyl)-1,5-diphenyl-1H-pyrazole-3- carbohydrazides 9a,b and 10, respectively, in good yields (65%-90%). The reactions of 3 with 4 and 8 in xylene for 8-15 h with catalytic amounts of base led to the formation of the products 5-7, 9, and 10. The structures of all new synthesized compounds were established by the 13C-NMR, 1H-NMR, IR spectroscopic data, and elemental analyses. TUeBITAK.
View MoreContact:+86-571-86217390
Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
Shandong Xingshun New Material Co., Ltd.
website:http://www.sd-xingshun.com
Contact:+86-519-86461196/+86-519-86464994
Address:Middle of Luhua East Road, Dingtao District
Xi'an Unique Electronic and Chemical Co., Ltd.
Contact:+86-029-88238008
Address:1703# B BUILDING WEST ELECTRONIC ZONE, XI'AN, CHINA
Compro Shijiazhuang Fine Chemical Co., Ltd
Contact:0086-311-89689838
Address:Economic and Technological Development Zone of Shijiazhuang,Hebei
Binzhou Holly Pharmaceutical Co.,Ltd.
Contact:74517
Address:No.15 Dapu Road,Huangpu District Shanghai,P.R.China
Doi:10.1021/jo102332e
(2011)Doi:10.1016/S0040-4039(00)88861-9
(1990)Doi:10.1007/s00044-011-9552-1
(2012)Doi:10.1021/ol200296j
(2011)Doi:10.2174/138620711794474033
(2011)Doi:10.1002/anie.201008199
(2011)