
Tetrahedron Letters p. 5235 - 5238 (1989)
Update date:2022-08-03
Topics:
Corey, E.J.
Huang, H.Ch.
A simple, enantiocontrolled and efficient route to an intermediate containing carbons 18 to 35 of the macrocyclic immunosuppressant FK-506 (1) is described which depends on a sequence of three enantioselective C-C bond forming reactions.
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(1989)