SYNTHESES OF 4-HYDROXY-5-IODO-2,3-DIMETHOXY-6-METHYLBENZOIC ACID AND 5-BROMO-4-HYDROXY-2,3-DIMETHOXY-6-METHYLBENZOIC ACID - AROMATIC CONSTITUENTS OF THE CALICHEMICINS

DOI: 10.1016/S0040-4020(01)89497-7

Source and publish data:

Tetrahedron p. 5511 - 5516 (1989)

Update date:2022-07-29

Topics:

Authors:

Laak, Kai van

Scharf, Hans-Dieter

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Article abstract of DOI:10.1016/S0040-4020(01)89497-7

4-Hydroxy-5-iodo-2,3-dimethoxy-6-methylbenzoic acid (1) and 5-bromo-4-hydroxy-2,3-dimethoxy-6-methylbenzoic acid (2) are the polysubstituted aromatic carboxylic acids found in calichemicin antibiotics.The title compounds are synthesized on preparative sca

Full text of DOI:10.1016/S0040-4020(01)89497-7

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