Tetrahedron Letters p. 7013 - 7016 (1989)
Update date:2022-08-02
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Bigge
Drummond
Johnson
In an NMDA specific receptor binding assay, 1 had lower affinity than its parent, APH. This result suggests that for competitive antagonists, diionization of the phosphonic acid moiety may be detrimental to receptor affinity.
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(2011)
