A new convenient procedure for the synthesis of pyrrolo[2,1-c][1,4] benzodiazepines

DOI: 10.1016/S0040-4039(00)73987-6

Source and publish data:

Tetrahedron Letters p. 5327 - 5328 (1993)

Update date:2022-07-29

Topics:

Authors:

Courtney, Stephen M.

Thurston, David E.

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Article abstract of DOI:10.1016/S0040-4039(00)73987-6

An efficient synthesis of the pyrrolo[2,1-c][1,4] (PBD) ring system based on a new cyclisation procedure is reported. The parent unsubstituted PBD (4a) and the benzyl derivative (4b) of the natural product DC-81 (4c) have been synthesized to illustrate the utility of this procedure.

Full text of DOI:10.1016/S0040-4039(00)73987-6

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