Tetrahedron p. 5709 - 5716 (1991)
Update date:2022-08-05
Topics: Regioselectivity Column chromatography Yield NMR spectroscopy Enantiomeric excess (ee) Catalytic hydrogenation Enantioselective synthesis Nucleophilic substitution Optical rotation Deprotection Precursor Asymmetric catalysis HPLC (high-performance liquid chromatography) Protecting group Isomer Chiral Resolution Chiral Auxiliary Racemic mixture Stereocenter
Buser
Pugin
Spindler
Sutter
The unchlorinated precursor 4 of CGA 80000 (1) was synthesized enantioselectively by two conceptionally different routes: a) by a 'chiral pool' approach starting from L-malic acid and b) by enantioselective hydrogenation of an enamide intermediate, catalyzed by chiral Rh- or Ru-phosphine-complexes.
View MoreTaixing Joxin Bio-tec Co.,Ltd.
website:http://www.joxbio.com
Contact:86-523-87558858 87612088
Address:No.88, chengdong industrial park
SHANGHAI GILEADER ADVANCE MATERIAL TECHNOLOGY CO.,LTD
website:http://www.tanguitech.com/contact.asp
Contact:+86-021-58692556
Address:No.6 Building,No. 668 Hengan RD Pudong,Shanghai
Contact:0510-85393305
Address:1619 Huishan Avenue, Huishan District, Wuxi,
website:http://www.arromax.com
Contact:+86-0512-62959601 skype:aimmezhang
Address:Suite 401, Bldg A3, 218 Xinghu St.Suzhou Industrial Park 215123, P.R. China
Xi'an caijing Opto-Electrical Science & Technology Co., LTD
Contact:+86-29-88294447
Address:NO.168 Zhangba Rd. East, Xi'an, P.R.China
Doi:10.1016/0040-4020(73)80130-9
(1973)Doi:10.1039/b208384a
(2002)Doi:10.1002/ejoc.200600082
(2006)Doi:10.1007/BF00901214
(1968)Doi:10.1021/om020992c
(2003)Doi:10.1021/jm00261a009
(1973)
