Tetrahedron p. 5709 - 5716 (1991)
Update date:2022-08-05
Topics: Regioselectivity Column chromatography Yield NMR spectroscopy Enantiomeric excess (ee) Catalytic hydrogenation Enantioselective synthesis Nucleophilic substitution Optical rotation Deprotection Precursor Asymmetric catalysis HPLC (high-performance liquid chromatography) Protecting group Isomer Chiral Resolution Chiral Auxiliary Racemic mixture Stereocenter
Buser
Pugin
Spindler
Sutter
The unchlorinated precursor 4 of CGA 80000 (1) was synthesized enantioselectively by two conceptionally different routes: a) by a 'chiral pool' approach starting from L-malic acid and b) by enantioselective hydrogenation of an enamide intermediate, catalyzed by chiral Rh- or Ru-phosphine-complexes.
View MorePharmaResources(Kaiyuan)CO,.Ltd
Contact:+86-21-50720028
Address:No.3, Beihuan Road, Economic Development District, Kaiyuan City, Tieling City, Liaoning Province, China 112300
Shanghai Science Peptide Biological Technology Co.,ltd
website:http://www.scipeptide.com
Contact:+86-21-51099675
Address:No.8 Changyang Rd
WuHan rongfashun BioChemical co., LTD
Contact:02788866139
Address:No.95 LuoYu Road,Wuhan
Contact:+86-158-05817090
Address:ROOM 9F, FLAT 2, GUODU DEVELOPING BLDG, No.182, ZHAOHUI ROAD
Xinjiang Fufeng Biotechnologies Co., Ltd.
Contact:+86-539-7287111
Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI
Doi:10.1016/0040-4020(73)80130-9
(1973)Doi:10.1039/b208384a
(2002)Doi:10.1002/ejoc.200600082
(2006)Doi:10.1007/BF00901214
(1968)Doi:10.1021/om020992c
(2003)Doi:10.1021/jm00261a009
(1973)
