Tetrahedron p. 1379 - 1384 (1990)
Update date:2022-07-31
Topics:
Bartoli, Giuseppe
Palmieri, Gianni
Petrini, Marino
The reaction of 2-trimethylsilylmethylanilides and esters in basic medium provides a new general method for the synthesis of indoles. The advantages of this method are the mild reaction conditions (-10-0°C), the ready availability of the starting materials and the use of a non-nucleophilic base (lithium 2,2,6,6-tetramethylpiperidide) to promote cyclisation.
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Doi:10.1016/S0223-5234(97)88913-1
(1997)Doi:10.1021/ol200389p
(2011)Doi:10.1002/adsc.201100366
(2012)Doi:10.1002/adsc.201000768
(2011)Doi:10.1016/S0040-4020(01)81371-5
(1990)Doi:10.1007/BF00963017
(1990)
