PREPARATION OF β-KETOMACROLACTONES AND β-KETODIOLIDES USING S-t-BUTYL 3-OXOBUTANETHIOATE AND S-t-BUTYL 4-DIETHYLPHOSPHONO-3-OXOBUTANETHIOATE

Article abstract of DOI:10.1016/S0040-4020(01)89218-8

Using S-t-butyl 3-oxobutanethioate (1) and S-t-butyl 4-diethylphosphono-3-oxobutanethioate (2) various homologation reactions with t-butyldimethylsilyl protected hydroxy-iodides and aldehydes are reported.The products of these reactions after deprotection