Solution synthesis of a dimeric pentapeptide: Diketopiperazine cyclisation of Glu-Asp dipeptide esters and Asp-racemisation during segment condensation

DOI: 10.1016/S0040-4020(01)85085-7

Source and publish data:

Tetrahedron p. 2277 - 2288 (1994)

Update date:2022-08-05

Topics: Characterization Protection of Functional Groups Deprotection and Purification

Authors:

Fischer Fischer

Solbakken

Undheim Undheim

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)85085-7

A haemoregulatory peptide analogue derived from the cystine-dimerised pentapeptide Glp-Glu-Asp-Cys-Lys-OH, in which the cystine residue has been replaced by an isosteric L,L-2,7-diaminosuberic acid moiety, was prepared by segment condensation in solution.

Full text of DOI:10.1016/S0040-4020(01)85085-7

Products guided by the article

Product name:L-Aspartic acid, N-[(phenylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) 1-(2-propenyl) ester

Cas No:127949-85-3

R&D Labs maybe for 127949-85-3

Changzhou LanXu Chemical Co.,ltd.(expird)

Contact:86-0519-86330911,13656129734,15261186386

Address:Room 524, Depart.Chemical, Changzhou Science and Eductaion town, Jiangsu, China;Factory: Haian Fine Chemical Industry Park,Nantong,Jiangsu,China
Hangzhou Hysen Pharma co.,Ltd.

website:http://www.hysenpharma.cn/

Contact:0086-571-88298791

Address:#701,Gudun Road Hangzhou
Tangshan Moneide Trading Co., Ltd.

Contact:+86-315-8309571

Address:2-7-420 Jidong Building Materials Commercial Center, Tangshan, Hebei, 064000 China
Zhejiang Golden-Shell Pharmaceutical Co.,Ltd.

Contact:+86-576-87501888 / 87501988

Address:No.89 Zhongxing Road. Li'ao, Yuhuan, Zhejiang, China
GUANGZHOU MEDCAN PHARMATECH LTD

website:http://www.gzmedcan.com

Contact:+86-20-82519649

Address:Building J,Room 101,1 JiangtashanRd,Guang Zhou Science City,Guang Zhou ,China

Relevant to this article

Oxidative Cyclization of β-Aminoacrylamides Mediated by PhIO: Chemoselective Synthesis of Isoxazoles and 2 H-Azirines

Doi:10.1021/acs.joc.8b02132
(2018)
Doi:10.1016/S0020-1693(00)84659-9
(1990)
Simple Analogues of Quaternary Benzo[ c]phenanthridine Alkaloids: Discovery of a Novel Antifungal 2-Phenylphthalazin-2-ium Scaffold with Excellent Potency against Phytopathogenic Fungi

Doi:10.1021/acs.jafc.0c06507
(2020)
Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential

Doi:10.1021/jm200592f
(2011)
Palladium-catalyzed asymmetric conjugate addition of arylboronic acids to heterocyclic acceptors

Doi:10.1002/chem.201203643
(2013)
Synthesis,¹¹B- and¹⁹F NMR spectroscopy, and optical and electrochemical properties of novel 9-aryl-3-(aryl/heteroaryl)-1,1-difluoro-7-(trifluoromethyl)-1H-[1,3,5,2]oxadiazaborinino[3,4-a][1,8]naphthyridin-11-ium-1-uide complexes

Doi:10.1016/j.tetlet.2016.09.068
(2016)

Article Doi