Journal of the Chemical Society. Perkin transactions I p. 579 - 584 (1992)
Update date:2022-08-02
Topics:
Brimble, Margaret A.
Nairn, Michael R.
A synthesis of pyranonaphthoquinone-spiroacetal 12 is reported which represents an efficient entry to the pentacyclic framework of the pyranonaphthoquinone antibiotic griseusin A.The key step involves assembly of the furo<3,2-b>naphtho<2,3-d>pyran 11 via a ceric ammonium nitrate oxidative rearrangement of the furo<3,2b>naphtho<2,1-d>furan 10.This latter heterocycle 10 in turn was constructed via the uncatalysed 1,4-addition of 2-trimethylsilyloxyfuran 9 to naphthoquinone 8.Naphthoquinone 8 is readily available from 1,4-dimethoxynaphthalene-2-carbaldehyde 3 and acetylene 4.
View Morewebsite:http://www.hope-chem.com
Contact:86-21-58090396-805
Address:Floor 4, Building 5, No.588 Tianxiong Road, Zhoupu International Medical Zone, ShangHai, China
Jiaxing Trustworthy Import And Export Co.,Ltd
Contact:+86-573-82030555
Address:Room 1202, Unit B, Charming plaza,No.1558 East Zhongshan Road , Jiaxing City, Zhejiang Province, China.
Jiangxi Hito Chemical Co., Ltd.
Contact:+86-792-3170318
Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
website:http://www.enbridgepharm.com
Contact:+86-510-83591909
Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China
Ningbo Inno Pharmchem Co., Ltd.
Contact:86-574-87319282
Address:6F-5,NO.163 RUIQING RD.,NINGBO 315000 CHINA
Doi:10.1021/jo00001a006
(1991)Doi:10.1016/j.jfluchem.2011.01.008
(2011)Doi:10.1021/ja00290a037
(1985)Doi:10.1080/00958972.2011.596934
(2011)Doi:10.1016/j.jorganchem.2014.01.023
(2014)Doi:10.1021/jo0701841
(2007)
