Tetrahedron Letters p. 3977 - 3980 (1996)
Update date:2022-07-31
Topics:
McGill, John M.
Labell, Elizabeth S.
Williams, MaryAnn
The reductive amination of substituted cyclohexanones with sodium triacyloxyborohydrides derived from NaBH4 and various carboxylic acids provides highly diastereoselective conversions to protected axial amines. This method was applied to the stereoselective preparation of 3-endo-tropanamine.
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