Nitrile Additions to C,N-Diacylimines. Formation of 4-Amidooxazoles

DOI: 10.1021/jo00305a015

Source and publish data:

Journal of Organic Chemistry p. 5225 - 5229 (1990)

Update date:2022-08-04

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Authors:

Fischer, Bilha

Hassner, Alfred

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Article abstract of DOI:10.1021/jo00305a015

Nitriles are shown to react with C,N-diacylimines 2, generated in situ from 1 or 4 in the presence of Lewis acids, to produce 4-amidooxazoles 5 and 6 in good to excellent yield.Diamides are sometimes also produced.The reaction was followed by NMR spectros

Full text of DOI:10.1021/jo00305a015

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