Discovery of highly potent and neurotensin receptor 2 selective neurotensin mimetics

DOI: 10.1021/jm200006c

Source and publish data:

Journal of Medicinal Chemistry p. 2915 - 2923 (2011)

Update date:2022-08-04

Topics:

Authors:

Einsiedel, Jürgen

Held, Cornelia

Hervet, Maud

Plomer, Manuel

Tschammer, Nuska

Hübner, Harald

Gmeiner, Peter

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Article abstract of DOI:10.1021/jm200006c

The neurotensin receptor subtype 2 (NTS2) is involved in the modulation of tonic pain sensitivity and psychiatric diseases and is, therefore, regarded as a highly attractive pharmacological target protein. Aiming to discover NTS2 selective ligands, we her

Full text of DOI:10.1021/jm200006c

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